目的：探索大数据时代综合医院的数据治理，促进智慧医院信息化医疗数据合理利用，推动智慧医院高质量发展。方法：通过分析综合医院信息化发展中数据治理的难点，建立统一明确的标准化数据架构，制定统一的指标体系，推行精细化的数据质量管理规范，并通过实际建设成效进行验证。结果：通过基于标准的数据治理，提高了医疗数据及其资源的管理水平，提升了临床研究效率，推动了医疗流程的优化。结论：大数据时代下智慧医院基于统一标准的数据治理，可复制推广，有助于数据要素发挥新质生产力乘数效应的经济效益和社会价值。

Objective Corresponding author: ZHANG Lei, Email: zhanglei@niha.org.cn To explore the data governance of general hospitals in the big data era, promote the rational utilization of information medical data in smart hospitals, and promote the high-quality development of smart hospitals. Methods By analyzing the difficulties of data governance in IT application development of general hospitals, a unified, clear and standardized data framework was established, a unified index system was formulated, and refined data quality management norms were implemented, which were verified by actual construction results. Results Through standards-based data governance, the management level of medical data and its resources was improved, the efficiency of clinical  research was enhanced, and the innovation of medical process and the optimization of medical model were promoted. Conclusion In the era of big data, the data governance of smart hospitals based on unified standards can be replicated and promoted, which can also help data elements realize the economic benefits and social value of the  multiplier effect of new productive force.